abstract：UNLABELLED:Neuropsychological studies of patients suffering from apraxia strongly imply a left hemisphere basis for skillful object use, the neural mechanisms of which, however, remain to be elucidated. We therefore carried out a PET study in 14 healthy human volunteers with the aim to isolate the neural mechanisms und...

journal_title：NeuroImage

authors： Rumiati RI,Weiss PH,Shallice T,Ottoboni G,Noth J,Zilles K,Fink GR

更新日期：2004-04-01 00:00:00

abstract：:White matter hyperintensities (WMHs) are commonly seen on brain magnetic resonance imaging (MRI) scans of elderly individuals, but their functional significance remains controversial. We used perfusion-weighted MRI to determine the impact of WMHs on cortical regional cerebral blood volume (rCBV). We studied 24 elderly...

journal_title：NeuroImage

authors： Wen W,Sachdev P,Shnier R,Brodaty H

更新日期：2004-04-01 00:00:00

abstract：:A key objective in neuroscience is to improve our understanding of the relationship between brain function and structure. We investigated this in the posterior visual pathways of healthy volunteers by applying functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) with tractography. The optic ...

journal_title：NeuroImage

authors： Toosy AT,Ciccarelli O,Parker GJ,Wheeler-Kingshott CA,Miller DH,Thompson AJ

更新日期：2004-04-01 00:00:00

abstract：:Hippocampal volume reductions are widely observed in schizophrenia. Some studies suggest anterior hippocampal regions are more susceptible and associated with frontal lobe dysfunctions, while others implicate posterior regions. Using high-resolution MR images and novel computational image analysis methods, we identifi...

journal_title：NeuroImage

authors： Narr KL,Thompson PM,Szeszko P,Robinson D,Jang S,Woods RP,Kim S,Hayashi KM,Asunction D,Toga AW,Bilder RM

更新日期：2004-04-01 00:00:00

abstract：:The modulation of repetition effects by the lag between first and second presentations of a visual object during a speeded semantic judgment task was examined using both scalp event-related potentials (ERPs) and event-related functional magnetic resonance imaging (efMRI). Four levels of lag were used within a single s...

journal_title：NeuroImage

authors： Henson RN,Rylands A,Ross E,Vuilleumeir P,Rugg MD

更新日期：2004-04-01 00:00:00

abstract：:The event-related optical signal (EROS) uses near-infrared light to study changes in neuronal optical properties in response to stimuli and endogenous events. EROS responses to electrical stimulation of the median nerve at 1, 5, and 8 Hz were collected from 80 channels in 7 subjects. Optical recording channels were sp...

journal_title：NeuroImage

authors： Maclin EL,Low KA,Sable JJ,Fabiani M,Gratton G

更新日期：2004-04-01 00:00:00

abstract：:Voxel-based morphometry (VBM) allows the output of structural data in a Statistical Parametric Map of the brain in the same way that the SPM can do with functional data. Using functional magnetic resonance (fMR), we studied brain activation in 14 patients with schizophrenia and 14 matched normal controls. We found sig...

journal_title：NeuroImage

authors： Salgado-Pineda P,Junqué C,Vendrell P,Baeza I,Bargalló N,Falcón C,Bernardo M

更新日期：2004-03-01 00:00:00

abstract：:To investigate the spatial and temporal changes in electro-cortical brain activity and hand kinematics during the acquisition of an internal model of a novel screen-cursor transformation, we employed single-trial infomax independent component analysis (ICA), spectral estimation, and kinematics methods. Participants pe...

journal_title：NeuroImage

authors： Contreras-Vidal JL,Kerick SE

更新日期：2004-03-01 00:00:00

abstract：:When functional neuroimaging researchers draw conclusions about the sensory, cognitive, or motor processes that are associated with changes in brain activity, they are making assumptions about the component processes involved in performing a complex behavioral task. We demonstrate the danger in making such assumptions...

journal_title：NeuroImage

authors： Meegan DV,Purc-Stephenson R,Honsberger MJ,Topan M

更新日期：2004-03-01 00:00:00

abstract：:Functional transcranial Doppler sonography (fTCD) adds to the techniques of functional imaging. fTCD measures cerebral perfusion changes related to neural activation in a way comparable to functional magnetic resonance tomography. fTCD contends itself with comparison of averaged, event-related blood flow velocity chan...

journal_title：NeuroImage

authors： Deppe M,Ringelstein EB,Knecht S

更新日期：2004-03-01 00:00:00

abstract：:Positive affect elicited in a mother toward her newborn infant may be one of the most powerful and evolutionarily preserved forms of positive affect in the emotional landscape of human behavior. This study examined the neurobiology of this form of positive emotion and in so doing, sought to overcome the difficulty of ...

journal_title：NeuroImage

authors： Nitschke JB,Nelson EE,Rusch BD,Fox AS,Oakes TR,Davidson RJ

更新日期：2004-02-01 00:00:00

abstract：:Humans can flexibly alter a plan of action to adjust their behavior adaptively in changing environments. Functional neuroimaging has shown distinct patterns of activation across a frontoparietal network responsible for switching and updating such plans of action or 'task sets.' However, little is known about the tempo...

journal_title：NeuroImage

authors： Periáñez JA,Maestú F,Barceló F,Fernández A,Amo C,Ortiz Alonso T

更新日期：2004-02-01 00:00:00

abstract：:Accurate appraisal of meaningful environmental signals involves the interpretation of salient information for their intrinsic emotional value and personal relevance. We examined the neural basis for these components of endogenous salience during such appraisals using trial-related functional magnetic resonance imaging...

journal_title：NeuroImage

authors： Phan KL,Taylor SF,Welsh RC,Ho SH,Britton JC,Liberzon I

更新日期：2004-02-01 00:00:00

abstract：:Segmentation and mapping of the human cerebral cortex from magnetic resonance (MR) images plays an important role in neuroscience and medicine. This paper describes a comprehensive approach for cortical reconstruction, flattening, and sulcal segmentation. Robustness to imaging artifacts and anatomical consistency are ...

journal_title：NeuroImage

authors： Tosun D,Rettmann ME,Han X,Tao X,Xu C,Resnick SM,Pham DL,Prince JL

更新日期：2004-01-01 00:00:00

abstract：:We argue that published results demonstrate that new insights into human brain function may be obscured by poor and/or limited choices in the data-processing pipeline, and review the work on performance metrics for optimizing pipelines: prediction, reproducibility, and related empirical Receiver Operating Characterist...

journal_title：NeuroImage

authors： Strother S,La Conte S,Kai Hansen L,Anderson J,Zhang J,Pulapura S,Rottenberg D

更新日期：2004-01-01 00:00:00

abstract：:We survey the recent activities of the Odyssée Laboratory in the area of the application of mathematics to the design of models for studying brain anatomy and function. We start with the problem of reconstructing sources in MEG and EEG, and discuss the variational approach we have developed for solving these inverse p...

journal_title：NeuroImage

authors： Faugeras O,Adde G,Charpiat G,Chefd'hotel C,Clerc M,Deneux T,Deriche R,Hermosillo G,Keriven R,Kornprobst P,Kybic J,Lenglet C,Lopez-Perez L,Papadopoulo T,Pons JP,Segonne F,Thirion B,Tschumperlé D,Viéville T,Wotawa N

更新日期：2004-01-01 00:00:00

abstract：:We use a computational neuroscience approach to study the role of feature-based attention in visual perception. This model is used to numerically simulate a visual attention experiment. The neurodynamical system consists of many interconnected modules that can be related to the dorsal and ventral paths of the visual c...

journal_title：NeuroImage

authors： Corchs S,Deco G

更新日期：2004-01-01 00:00:00

abstract：:It is currently unclear whether impairment of the cholinergic system is present in Alzheimer disease (AD) already at an early stage and to what extent it depends on degeneration of the nucleus basalis of Meynert (nbM). We examined acetylcholine esterase activity in vivo in the nbM, the amygdala, and cerebral neocortex...

journal_title：NeuroImage

authors： Herholz K,Weisenbach S,Zündorf G,Lenz O,Schröder H,Bauer B,Kalbe E,Heiss WD

更新日期：2004-01-01 00:00:00

abstract：:The differentiation of multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) from idiopathic Parkinson's disease (IPD) is difficult. Magnetization transfer imaging (MTI), a measure that correlates with myelination and axonal density, was employed in this study in the attempt to distinguish between the...

journal_title：NeuroImage

authors： Eckert T,Sailer M,Kaufmann J,Schrader C,Peschel T,Bodammer N,Heinze HJ,Schoenfeld MA

更新日期：2004-01-01 00:00:00

abstract：:The identification of brain systems contributing to different aspects of visuospatial attention is of both clinical and theoretical interest. Cued target detection tasks provide a simple means to dissociate attentional subcomponents, such as alerting, orienting or reorienting of attention. Event-related functional mag...

journal_title：NeuroImage

authors： Thiel CM,Zilles K,Fink GR

更新日期：2004-01-01 00:00:00

abstract：:It is not currently known whether subjects can learn to voluntarily control activation in localized regions of their own brain using neuroimaging. Here, we show that subjects were able to learn enhanced voluntary control over task-specific activation in a chosen target region, the somatomotor cortex. During an imagine...

journal_title：NeuroImage

authors： deCharms RC,Christoff K,Glover GH,Pauly JM,Whitfield S,Gabrieli JD

更新日期：2004-01-01 00:00:00

abstract：:With this study, we explored the blood oxygen level-dependent responses within the temporal lobe to short auditory stimuli of different classes. To address this issue, we performed an attentive listening event-related fMRI study, where subjects were required to concentrate during the presentation of different types of...

journal_title：NeuroImage

authors： Specht K,Reul J

更新日期：2003-12-01 00:00:00

abstract：:A new functional MRI protocol that integrates variable echo time (TE) acquisition and a block-design paradigm is proposed and evaluated with finger-tapping motor task. Simulations and experimental data show that the blood oxygenation level-dependent (BOLD) sensitivity achieved with this approach is comparable to that ...

journal_title：NeuroImage

authors： Chen NK,Egorova S,Guttmann CR,Panych LP

更新日期：2003-12-01 00:00:00

abstract：:Our objective was to investigate correlations between clinical motor scores and cerebral sensorimotor activation to demonstrate that this reorganization is the neural substratum of motor recovery. Correlation analyses identified reorganization processes shared by all patients. Nine patients with first-time corticospin...

journal_title：NeuroImage

authors： Loubinoux I,Carel C,Pariente J,Dechaumont S,Albucher JF,Marque P,Manelfe C,Chollet F

更新日期：2003-12-01 00:00:00

abstract：:The goal of the MEG study was to investigate the influence of tumor treatment on pathological delta activity (1-4 Hz). The treatment consisted of neurosurgery, and in some of the patients, additional radiotherapy. MEG and MR recordings were made both before and after the treatment in 17 patients. The signal power in t...

journal_title：NeuroImage

authors： de Jongh A,Baayen JC,de Munck JC,Heethaar RM,Vandertop WP,Stam CJ

更新日期：2003-12-01 00:00:00

abstract：:Recent atlases of the cortical surface are based on a modelization of the cerebral cortex as a topological sphere. This captures effectively its organization as a regular bidimensional sheet of layers parallel to the surface and with perpendicular cortical columns. Yet, while in the vertical direction cortices are alm...

journal_title：NeuroImage

authors： Toro R,Burnod Y

更新日期：2003-11-01 00:00:00

abstract：:The magnetic resonance imaging (MRI)-detectable T1 contrast agent manganese (Mn2+) has recently been introduced as a neural tracer in rodents, birds, and monkeys. We have tested to what extent this in vivo method is useful for three-dimensional (3-D) survey of connectivity patterns in the rat somatosensory system. A c...

journal_title：NeuroImage

authors： Leergaard TB,Bjaalie JG,Devor A,Wald LL,Dale AM

更新日期：2003-11-01 00:00:00

abstract：:The secondary somatosensory cortex (SII) is strongly involved in the processing of somatosensory tactile and nociceptive sensations. We investigated the effect on SII responses of simultaneous painful and nonpainful electrical stimulations delivered to the thumb and little finger. According to the "bimodal" (i.e., noc...

journal_title：NeuroImage

authors： Torquati K,Pizzella V,Della Penna S,Franciotti R,Babiloni C,Romani GL,Rossini PM

更新日期：2003-11-01 00:00:00

abstract：:We describe Surface Editor-a tool for interactive specification of regions of interest (ROIs) on brain surfaces. The tool allows users to define subsurfaces by tracing around areas within a triangle-mesh brain surface. The input to the program is a triangle-mesh representation of a brain volume and a set of user-defin...

journal_title：NeuroImage

authors： Shiffman S,Ng YR,Brosnan TJ,Eliez S,Links JM,Kelkar UV,Reiss AL

更新日期：2003-11-01 00:00:00

abstract：:The two commonest, clinically well-defined, forms of parkinsonism are idiopathic Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Both involve, inter alia, pathological changes in the substantia nigra pars compacta (SN(C)). In PD there is neuronal loss with associated Lewy body pathology and microgli...

journal_title：NeuroImage

authors： Hutchinson M,Raff U,Lebedev S

更新日期：2003-11-01 00:00:00

abstract：:Left inferior parietal lobe lesions can cause perturbation of the space-time plans underlying skilled actions. But does the perceptual integration of spatiotemporal information use the same neural substrate or is the role of the left inferior parietal cortex restricted to visuomotor transformations? We use fMRI and a ...

journal_title：NeuroImage

authors： Assmus A,Marshall JC,Ritzl A,Noth J,Zilles K,Fink GR

更新日期：2003-11-01 00:00:00

abstract：:Identification of spatiotemporal interactions within/between neuron populations is critical for detection and characterization of large-scale neuronal interactions underlying perception, cognition, and behavior. Univariate analysis has been employed successfully in many neuroimaging studies. However, univariate analys...

journal_title：NeuroImage

authors： Lin FH,McIntosh AR,Agnew JA,Eden GF,Zeffiro TA,Belliveau JW

更新日期：2003-10-01 00:00:00

abstract：:Cortical activity evoked by repeated identical sensory stimulation is extremely variable. The source of this variability is often assigned to "random ongoing background activity" which is considered to be irrelevant to the processing of the stimuli and can therefore be eliminated by ensemble averaging. In this work, w...

journal_title：NeuroImage

authors： Laskaris NA,Liu LC,Ioannides AA

更新日期：2003-10-01 00:00:00

abstract：:The outcome of Statistical Parametric Mapping (SPM) analyses of PET activation studies depends among others, on the quality of reconstructed data. In general, filtered back-projection (FBP) is used for reconstruction in PET activation studies. There is, however, increasing interest in iterative reconstruction algorith...

journal_title：NeuroImage

authors： Mesina CT,Boellaard R,van den Heuvel OA,Veltman DJ,Jongbloed G,van der Vaart AW,Lammertsma AA

更新日期：2003-10-01 00:00:00

abstract：:We used functional magnetic resonance imaging (fMRI) to assess cortical activations associated with increasing task difficulty (TD) in a visuospatial paired associates learning task. Encoding and retrieval were examined when 100% successful retrieval of three, four, or six object-location pairs had been attained (thus...

journal_title：NeuroImage

authors： Gould RL,Brown RG,Owen AM,ffytche DH,Howard RJ

更新日期：2003-10-01 00:00:00

abstract：:In this study we examined spatiotemporal profiles of brain activity in the context of tasks designed to engage different verbal learning strategies (serial order, phonological, and semantic). The profile of activation associated with the serial-order strategy, which resulted in poor recall performance, featured early ...

journal_title：NeuroImage

authors： Maestú F,Simos PG,Campo P,Fernández A,Amo C,Paul N,González-Marqués J,Ortiz T

更新日期：2003-10-01 00:00:00

abstract：:The study of congenitally deaf individuals provides a unique opportunity to understand the organization and potential for reorganization of human auditory cortex. We used magnetic resonance imaging (MRI) to examine the structural organization of two auditory cortical regions, Heschl's gyrus (HG) and the planum tempora...

journal_title：NeuroImage

authors： Penhune VB,Cismaru R,Dorsaint-Pierre R,Petitto LA,Zatorre RJ

更新日期：2003-10-01 00:00:00

abstract：:The effects of functional magnetic resonance imaging (fMRI) acoustic noise were investigated on the parameters of event-related responses (ERPs) elicited during auditory matching-to-sample location and pitch working memory tasks. Stimuli were tones with varying location (left or right) and frequency (high or low). Sub...

journal_title：NeuroImage

authors： Novitski N,Anourova I,Martinkauppi S,Aronen HJ,Näätänen R,Carlson S

更新日期：2003-10-01 00:00:00

abstract：:Functional MRI studies are very sensitive to motion; head movements of as little as 1-mm translations or 1 degrees rotations may cause spurious signals. An algorithm was developed that uses k-space MRI data to monitor subject motion during functional MRI time series. A k-space weighted average of squared difference be...

journal_title：NeuroImage

authors： Caparelli EC,Tomasi D,Arnold S,Chang L,Ernst T

更新日期：2003-10-01 00:00:00

abstract：:Neocortical cholinergic afferents are proposed to influence both selective attention and emotional processing. In a study of healthy adults we used event-related fMRI while orthogonally manipulating attention and emotionality to examine regions showing effects of cholinergic modulation by the anticholinesterase physos...

journal_title：NeuroImage

authors： Bentley P,Vuilleumier P,Thiel CM,Driver J,Dolan RJ

更新日期：2003-09-01 00:00:00